Welcome to The Twisted Tuna of Port Salerno Florida! We are the largest family owned and operated waterfront restaurant in Martin County and home to the famous Port Salerno Seafood Festival. With over 10,000 sqft of indoor dining space on two floors, The Twisted Tuna can accommodate functions of almost any size. We serve lunch and dinner 7 days a week and host a Bloody Mary Brunch on Sundays. The Twisted Tuna has 3 full liquor bars including our main bar featuring many flat screen TVs, our second floor Tito's® Bloody Mary Bar and our outdoor Bud Light® Bar. The restaurant is perfectly situated on the beautiful Manatee Pocket and has several outdoor waterfront dining areas that are both smoking and pet friendly. Taking only the best from our previous South Florida restaurants, we have created a slightly twisted menu featuring the freshest seafood dishes, just the right amount of traditional Italian favorites and the finest sushi and raw bar selections available today.